Toshiyuki Takahashi Selected Research

Therapeutics

4/2024	Two Cases of Aquaporin-4 and Myelin Oligodendrocyte Glycoprotein Immunoglobulin G Double-Positive Optic Neuritis Successfully Treated With Steroid Therapy.
3/2024	Evaluation of Steroid Pulse Therapy Responsiveness in Myelin-Oligodendrocyte Glycoprotein Antibody-Positive Optic Neuritis.
2/2024	Clinical Features of 544 Patients With Ruptured Aortic Aneurysm　- A Report From the Tokyo Acute Aortic Super Network Database.
11/2022	Cooccurrence of Alport syndrome and poststreptococcal acute glomerulonephritis with improvement after steroid administration.
4/2021	Optimal management of neuromyelitis optica spectrum disorder with aquaporin-4 antibody by oral prednisolone maintenance therapy.
1/2021	Early Treatment Initiation With Oral Prednisolone for Relapse Prevention Alleviates Depression and Fatigue in Aquaporin-4-Positive Neuromyelitis optica Spectrum Disorder.
1/2021	Optic neuritis after ocular trauma in anti-aquaporin-4 antibody-positive neuromyelitis optica spectrum disorder.
1/2021	[A case of meningoencephalitis that developed during nivolumab use].
10/2020	MOG-Ab titer-guided approach for steroid tapering to prevent relapse in children with mog antibody-associated adem diseases: A case report.
6/2020	Epilepsia Partialis Continua as an Early Sign of Anti-Myelin Oligodendrocyte Glycoprotein Antibody-positive Encephalitis.

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Toshiyuki Takahashi Research Topics

Disease

74	Neuromyelitis Optica (Devic's Disease) 07/2023 - 05/2007
45	Optic Neuritis (Retrobulbar Neuritis) 04/2024 - 01/2011
26	Multiple Sclerosis 01/2023 - 02/2009
21	Demyelinating Diseases (Demyelinating Disease) 01/2023 - 09/2010
19	Encephalitis (Encephalitis, Rasmussen) 01/2023 - 11/2009
19	Myelitis 01/2023 - 02/2008
14	Neoplasms (Cancer) 01/2021 - 07/2003
13	Acute Disseminated Encephalomyelitis (Postinfectious Encephalomyelitis) 01/2023 - 03/2015
12	Myocardial Infarction 01/2015 - 03/2002
10	Pain (Aches) 07/2023 - 09/2002
9	Heart Failure 01/2021 - 01/2003
8	Spinal Cord Diseases 01/2024 - 04/2002
7	Leukocytosis (Pleocytosis) 06/2020 - 05/2012
7	Transverse Myelitis (Necrotizing Myelitis) 10/2019 - 02/2009
6	Disease Progression 02/2024 - 09/2011
6	Inflammation (Inflammations) 01/2024 - 05/2004
6	Infections 01/2023 - 01/2012
6	Hypertrophy 01/2023 - 01/2003
6	Hypertension (High Blood Pressure) 01/2022 - 01/2007
6	Fibrosis (Cirrhosis) 02/2018 - 05/2003
6	Ventricular Remodeling 01/2011 - 04/2003
6	Infarction (Infarctions) 02/2009 - 01/2003
5	Kyphosis 03/2024 - 08/2016
5	Nephrotic Syndrome (Syndrome, Nephrotic) 10/2023 - 01/2019
5	Hypoxia (Hypoxemia) 01/2021 - 04/2005
5	Obesity 10/2012 - 01/2007
4	Cysts 02/2024 - 06/2010
4	Hypesthesia (Numbness) 01/2024 - 09/2011
4	Intervertebral Disc Displacement (Herniated Disc) 01/2023 - 02/2018
4	Radiculopathy (Radiculopathy, Cervical) 01/2023 - 10/2020
4	Left Ventricular Dysfunction 01/2021 - 03/2005
4	Autoimmune Diseases (Autoimmune Disease) 01/2020 - 02/2003
4	Cognitive Dysfunction 05/2019 - 10/2012
4	Cicatrix (Scar) 02/2018 - 02/2009
4	Adenocarcinoma 12/2016 - 09/2003
4	Disorders of Excessive Somnolence (Hypersomnia) 06/2015 - 08/2011
4	Hemorrhage 01/2015 - 03/2002
4	Necrosis 08/2011 - 02/2009
4	Heart Rupture 12/2010 - 01/2003
4	Body Weight (Weight, Body) 08/2009 - 07/2008
3	Aneurysm (Aneurysms) 02/2024 - 07/2011
3	Aseptic Meningitis 09/2023 - 01/2013
3	Inappropriate ADH Syndrome (SIADH) 01/2023 - 08/2011
3	Seizures (Absence Seizure) 12/2022 - 06/2020
3	Death (Near-Death Experience) 01/2021 - 02/2009
3	Encephalomyelitis (Myeloencephalitis) 01/2020 - 08/2011
3	Epilepsy (Aura) 11/2019 - 10/2018
3	Opticospinal Multiple Sclerosis 12/2018 - 02/2009
3	Central Nervous System Diseases (CNS Diseases) 11/2018 - 10/2015
3	Coronary Artery Disease (Coronary Atherosclerosis) 11/2018 - 04/2013
3	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 12/2015 - 11/2009
3	Carcinoma (Carcinomatosis) 05/2015 - 11/2008
3	Unstable Angina 07/2013 - 09/2002
3	Abdominal Aortic Aneurysm 10/2011 - 07/2011

Drug/Important Bio-Agent (IBA)

52	Myelin-Oligodendrocyte GlycoproteinIBA 04/2024 - 02/2014
40	AntibodiesIBA 07/2023 - 02/2009
26	Immunoglobulin G (IgG)IBA 04/2024 - 05/2007
18	SteroidsIBA 04/2024 - 12/2003
17	AutoantibodiesIBA 05/2021 - 02/2003
17	Aquaporin 4IBA 01/2021 - 02/2009
13	anti-aquaporin 4 autoantibodyIBA 04/2019 - 03/2009
10	Proteins (Proteins, Gene)FDA Link 01/2020 - 02/2005
8	Biomarkers (Surrogate Marker)IBA 01/2023 - 09/2010
7	Adrenal Cortex Hormones (Corticosteroids)IBA 10/2020 - 12/2003
7	Messenger RNA (mRNA)IBA 01/2016 - 10/2004
7	C-Reactive ProteinIBA 05/2013 - 01/2003
6	CytokinesIBA 01/2021 - 04/2003
6	Methylprednisolone FDA LinkGeneric 01/2020 - 05/2008
5	Rituximab (Mabthera)FDA Link 01/2022 - 07/2011
5	Glucose (Dextrose)FDA LinkGeneric 10/2019 - 04/2005
5	Aquaporins (Water Channels)IBA 01/2018 - 05/2007
4	Myelin Basic ProteinIBA 12/2022 - 05/2012
4	Retinaldehyde (Retinal)IBA 01/2022 - 12/2010
4	Prednisolone (Predate)FDA LinkGeneric 04/2021 - 12/2007
4	Complement System Proteins (Complement)IBA 01/2021 - 03/2009
4	Interleukin-6 (Interleukin 6)IBA 01/2021 - 12/2008
4	AlbuminsIBA 01/2018 - 01/2007
4	OrexinsIBA 06/2015 - 08/2011
4	CollagenIBA 11/2011 - 02/2003
3	Vasopressins (Vasopressin)IBA 01/2023 - 08/2011
3	Dimethyl FumarateIBA 05/2022 - 10/2019
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 02/2022 - 10/2011
3	salicylhydroxamic acid (SHAM)IBA 01/2022 - 01/2005
3	CreatinineIBA 01/2021 - 01/2007
3	Oligoclonal BandsIBA 09/2018 - 01/2011
3	Insulin (Novolin)FDA Link 01/2015 - 07/2008
3	Glial Fibrillary Acidic ProteinIBA 08/2014 - 05/2008
3	AntigensIBA 09/2011 - 01/2006
3	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 08/2011 - 10/2008
3	Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link 03/2008 - 04/2005
3	CalciumIBA 08/2006 - 01/2003

Therapy/Procedure

40	Therapeutics 04/2024 - 03/2002
16	Decompression 09/2023 - 04/2002
10	Laminectomy 01/2024 - 03/2008
7	Percutaneous Coronary Intervention 01/2021 - 11/2009
5	Conservative Treatment 02/2024 - 01/2011
4	Immunotherapy 06/2020 - 07/2003
3	Operative Surgical Procedures 02/2024 - 09/2019
3	Radiotherapy 09/2023 - 09/2005
3	Catheters 01/2022 - 01/2014